Transplantation of organs from deceased donors with cancer
Advice just published by the Advisory Committee on the Safety of Blood, Tissues and Organs (SaBTO)
SaBTO has reviewed the use of organs for transplantation from
donors with cancer or a history of cancer, and drawn up
evidence-based recommendations to guide decision making.
People with cancer are not usually considered as potential organ
donors because of the risk of transmitting the malignancy. The risk
varies widely, however, depending on the nature of the cancer in
question. In certain circumstances it may still be possible
to carry out the wishes of this group of donors, and there is value
in evidence-based guidance which transplant surgeons can use when
deciding whether it would be to their patient's benefit to accept
an organ from a donor with cancer.
SaBTO's Working Group reviewed the literature and also analysed
data from the UK National Transplant Registry relating to the
outcomes of transplants from donors with a history of cancer.
Based on this evidence, they have categorised a number of
cancers according to their risk of transmission to an organ
recipient, and drawn up a series of recommendations.
SaBTO is keen to make its findings and advice widely known, so
that patients and transplant practitioners can benefit from them.
The report and recommendations